Fatty acids and their intermediates and derivatives have been recognized as crucial mediators of brain health. Consequently, disturbances in brain fatty acid metabolism are highly implicated in different aspects of neuronal dysfunction.
The thematic area of FAT4BRAIN is focused on the pivotal and common role of mitochondria-related fatty acid metabolism for the development of neurological disorders, a topic of highest biomedical and societal concern. The concerted research activities aim at deciphering novel mechanisms and developing new treatment strategies against these devastating diseases.
Virtual training on high-resolution respirometryTraining in high-resolution respirometry (HRR) for the assessment of mitochondrial energetics took place online on March 3-4, 2021
During training young investigators performed instrument set-up and experiment with permeabilized cells on O2ks under supervision provided online by Oroboros Instruments exprienced researcher.
Training also involved a basal education in respiratory concepts and approaches and specific training in the use of substrate-uncoupler-inhibitor-titration (SUIT) protocols for the evaluation of respiratory parameters in intact and permeabilised cells with focus on fatty acid metabolism assessment. Based on new protocols recently developed by the science team at Oroboros Intruments, the researcher learned how to apply HRFR in studies on cell culture, as well as preclinical and clinical samples.
Training on scientific writingProf. Helgi Schiöth will be holding the FAT4BRAIN workshop with the topic scientific writing on October 22, 2020
Prof. Helgi Schiöth leads the unit of Functional Pharmacology at Uppsala. His research involves investigating pharmacological, genetic and behavioural aspects as well as translational neurometabolic research and central regulation of food intake across species. Professor Schiöth has been continuously listed among the worlds “most influential researchers/scientific minds” based on citations from the last 10 years. His publication and citation summary comprise a total of 411 papers in peer-reviewed journals on PubMed with over 360 original articles and 50 reviews and more than 30,000 citations overall. He published in highly ranking journals such as PNAS, Alzheimers & Dementia, Nature Reviews Neuroscience and Nature Reviews Drug Discovery.
With his great experience in this area, we are happy to announce that Prof. Helgi Schiöth will be holding the FAT4BRAIN workshop with the topic scientific writing on October 22, 2020. The workshop will be divided into two sections, a morning session with focus on evaluation techniques for junior scientists and an afternoon session with a lecture about scientific writing and Q/A for both junior and senior scientists. Evaluation of scientific texts is a key challenge within scientific writing and effective self evaluation is very important. Furthermore, scientific writing is not only about writing scientific articles, it is in general important for how research is communicated effectively. The purpose of this FAT4BRAIN workshop is to increase awareness and recognition of what constitutes a good scientific writing and to point out common pitfalls and mistakes during the process.