Conferences

2022

  1. Dambrova M. Acylcarnitines in health and disease: biomarkers and drug targets. 7th Congress of Pharmacy in North Macedonia with international participation „Modern Trends in Pharmacy Opportunities and Challenges”, October 5-9, 2022, Ohrid, North Macedonia, oral presentation.

  2. Liepins E. Fatty acid metabolism in health and diseases. A4L_ACTIONS Thematic Mini-conference with Matchmaking Event „Cancer and Metabolic Disorders”, October 3-5, 2022, Smolenice, Slovakia, oral presentation.

  3. Gukālova B, Grīnberga S, Križanovska V, Sevostjanovs E, Dambrova M, Liepiņš E. LC–MS/MS analysis of omega-3 polyunsaturated fatty acids and their acylcarnitines in blood plasma. 2nd Drug Discovery Conference 2022, September 22-24, 2022, Riga, Latvia.

  4. Liepins E, Svalbe B, Cirule H, Videja M, Dambrova M. Arrest of long-chain acylcarnitine synthesis prevents inflammation and insulin resistance in adipose tissue of high-fat diet-fed TMLHE knockout mice. 58 th EASD Annual Meeting of the European Association for the Study of Diabetes. Stockholm, Sweden, September 19-23, 2022. In: https://doi.org/10.1007/s00125-022-05755-w (short oral presentation).

  5. Videja M, Makrecka-Kuka M, Korzh S, Sevostjanovs E, Cirule H, Liepinsh E, Dambrova M. Accumulation of trimethylamine N-oxide in renal tissue induces mitochondrial dysfunction in insulin-resistant mice. 58 th EASD Annual Meeting of the European Association for the Study of Diabetes. Stockholm, Sweden, September 19-23, 2022, In: https://doi.org/10.1007/s00125-022-05755-w (short oral presentation).

  6. Dambrova M, Vilskersts R, Liepinsh E. Mitochondrial metabolites acylcarnitines: therapeutic potential and drug targets. Bioblast 2022: BEC Inaugural Conference.  Innsbruck, Austria, June 29-30, 2022, oral presentation.

  7. Liepiņš E, Dambrova M. Long-chain acylcarnitines: from mitochondrial metabolism to clinical applications. FEBS3+ Conference of  Estonian, Latvian and Lithuanian Biochemical Societies, Tallinn, Estonia, June 15-17, 2022. Abstract book P. 72-73, oral presentation.

  8. Vavers E, Stelfa G, Svalbe B, Zvejniece L, Dambrova1 M. Interaction between sigma-1 and GABA-B receptors: evidence from sigma-1 receptor knockout mice. FEBS3+ Conference of  Estonian, Latvian and Lithuanian Biochemical Societies, Tallinn, Estonia, June 15-17, 2022. Abstract book P. 52-53, oral presentation.

  9. Miteniece A, Švalbe B, Vāvers E, Štelfa G, Lauberte L, Dambrova M, Zvejniece L. The evaluation of long-term neurological disabilities in mice after traumatic brain injury. FAT4BRAIN, International summer school in functional pharmacology, Riga, Latvia, June 6-10, 2022, oral presentation.

  10. Videja M, Sevostjanovs E, Upmale-Engela S, Liepinsh E, Konrade I and Dambrova M. Fasting-Mimicking Diet Reduces Trimethylamine N-Oxide Levels and Improves Serum Biochemical Parameters in Healthy Volunteers. FAT4BRAIN, International summer school in functional pharmacology, Riga, Latvia, June 6-10, 2022.  

  11. Stelga G, Svalbe B, Vavers E, Zvejniece L, Dambrova M. Time-dependent development of remote pain sensitisation following the TBI in mice. FAT4BRAIN, International summer school in functional pharmacology, Riga, Latvia, June 6-10, 2022.  

  12. Miteniece A, Švalbe B, Vāvers E, Štelfa G,Makrecka-Kūka M, Dambrova M, Zvejniece L. Genetic inactivation of sigma-1 receptor induces white adipocyte hypertrophy and changes in lipid and energy metabolism in mice. FAT4BRAIN, International summer school in functional pharmacology, Riga, Latvia, June 6-10, 2022.

     

  13. Dambrova M, Liepinsh E. Acylcarnitines in health and disease. FAT4BRAIN Workshop on mitochondrial function in CNS-related applications: from pre-clinical to clinical studies, Innsbruck, Austria, May 2-3, oral presentation.

  14. Stelfa G, Svalbe B, Vavers E, Zvejniece L, Dambrova M. Mitochondrial function in experimental traumatic brain injury. FAT4BRAIN Workshop on mitochondrial function in CNS-related applications: from pre-clinical to clinical studies, Innsbruck, Austria, May 2-3, 2022, oral presentation.

  15. Videja M, Dambrova M, Liepinsh E. Low-intensity exercise stimulates bioenergetics and increases fat oxidation in mitochondria of blood mononuclear cells from sedentary adults. FAT4BRAIN Workshop on mitochondrial function in CNS-related applications: from pre-clinical to clinical studies, Innsbruck, Austria, May 2-3, oral presentation.

  16. Videja M, Makrecka-Kuka M, Korzh S, Sevostjanovs E, Cirule H, Liepinsh E, Dambrova M. Accumulation of trimethylamine N-oxide in renal tissue induces mitochondrial dysfunction in insulin-resistant mice. 58 th EASD Annual Meeting of the European Association for the Study of Diabetes. Stockholm, Sweden, September 19-23, 2022. In: https://doi.org/10.1007/s00125-022-05755-w (short oral presentation).

  17. Liepins E, Svalbe B, Cirule H, Videja M, Dambrova M. Arrest of long-chain acylcarnitine synthesis prevents inflammation and insulin resistance in adipose tissue of high-fat diet-fed TMLHE knockout mice. 58 th EASD Annual Meeting of the European Association for the Study of Diabetes. Stockholm, Sweden, September 19-23, 2022. In: https://doi.org/10.1007/s00125-022-05755-w (short oral presentation).

  18. Vavers E, Stelfa G, Svalbe B, Miteniece A, Zvejniece L, Dambrova M. The in vivo interaction between sigma-1 and GABA-B receptors reveals new opportunities for the development of novel anti-seizure drugs. Drug Discovery Conference 2022. Riga, Latvia, September 22-24, 2022.

     

2021

  1. Vavers E, Stelfa G, Svalbe B, Vilks K, Zvejniece L, Dambrova M. Reduced expression of the R2 subunit of metabotropic GABA receptors in habenula is associated with increased seizure susceptibility in sigma-1 receptor knockout mice. Rudolf Buchheim 200 Conference “Rudolf Buchheim 200: New Essays on the Doctrine of Drugs”, September 9-11, 2021, Tartu, Estonia. Abstract book P. 47. 

  2. Svalbe B, Vavers E, Stelfa G, Zvejniece L, Dambrova M. Metabolic changes and reduced depression-like behaviour in sigma-1 receptor KO mice. The first of the ESN-ISN advanced school “From Neurodegeneration to Neural Carcinogenesis: Mechanisms and Common Biologies”. September 19-26, 2021, the Biomedical Research Foundation of the Academy of Athens (BRFAA), Athens, Greece.

  3. Svalbe B, Vavers E, Dambrova M, Zvejniece L, Makrecka-Kuka M. The sexual behaviour and functionality of spermatozoal mitochondria in Sigma-1 knockout mice.  3rd European Symposium on the "Physiopathology of Sigma-1 Receptors”. October 7-9, 2021, Bari, Italy. Abstract book P. 14.

  4. Stelfa G, Vavers E, Svalbe B, Serzants R, Grinberga S, Gukalova B, Dambrova M, Zvejniece L. Amelioration of neurobehavioral deficits after traumatic brain injury in sigma-1 receptor knockout mice. 3rd European Symposium on the "Physiopathology of Sigma-1 Receptors”. October 7-9, 2021, Bari, Italy. Abstract book P. 26.

  5. Zvejniece L, Svalbe B, Stelfa G, Zvejniece B, Vavers E, Dambrova M. Metabolomic profiling of Sigma-1 receptor knock-out mice. 3rd European Symposium on the "Physiopathology of Sigma-1 Receptors”. October 7-9, 2021, Bari, Italy. Abstract book P. 21

  6. Sizovs, A., Serzants,R.,  Dambrova, M. Towards Tumour-selective Nanomedicines Using Stealth Particles. International Congress of „Apollonia” University from Iași, March 1-3, 2021, lași, Romania
  7. Vilks K, Videja M, Makrecka-Kuka M, Katkevics M, Grandane A, Dambrova M, Liepinsh E. Long-chain acylcarnitines decrease the phosphorylation of the insulin receptor and Protein kinase B through a PTP1B-dependent mechanism.  Latvian Biochemical society (LaBS) and 79th International Scientific Conference of the University of Latvia section of Molecular biology. February 26, 2021. University of Latvia, Riga, Latvia.

  8. Svalbe B, Vavers E, Dambrova M, Zvejniece L, Makrecka-Kuka M. The functionality of spermatozoal mitochondria in sigma-1 receptor knockout mice. Latvian Biochemical society (LaBS) and 79th International Scientific Conference of the University of Latvia section of Molecular biology. February 26, 2021. University of Latvia, Riga, Latvia.

  9. Makrecka-Kuka M, Korzh S, Videja M, Dambrova M, Liepinsh E. Oxidative phosphorylation and fatty acid oxidation: who determines macrophage polarization? Virtual Keystone Symposium Integrating Metabolism and Immunity, January 25-28, 2021

2020

  1. Videja M, Sevostjanovs E, Konrade I, Dambrova M. 5-day intermittent fasting reduces proatherogenic metabolite trimethylamine N-oxide level and improves serum biochemical parameters. 3rd International Conference «Nutrition and Health», Riga, Latvia. Online. December 9-11, 2020. Abstract book page 93.

  2. Svalbe B, Makrecka-Kuka M, Vavers E, Dambrova M, Zvejniece L. The effect of sexual activity on mice spermatozoa mitochondrial functionality. Digital Andrology 2020, 5–9 December 2020. Abstract No P5.8; Abstract book page 46 https://www.kup.at/kup/pdf/14841.pdf

  3. Makrecka-Kuka M, Korzh S, Liepinsh E. Dynamics of metabolic choices in macrophages under pro-inflammatory activation. 4th Annual UCLA Mitochondria Symposium - Los Angeles, CA. Online. November 5-6, 2020

  4. Makrecka-Kuka M, Vilks K, Dambrova M, Liepinsh E. Lower cardiac content of long-chain acylcarnitines prevents ischemia-reperfusion-induced mitochondrial and cardiac damage in N6-trimethyllysine dioxygenase knockout mice. 4th Annual UCLA Mitochondria Symposium - Los Angeles, CA. Online. November 5-6, 2020

  5. Videja M, Vilskersts R, Korzh S, Cirule H, Sevostjanovs E, Dambrova M, Makrecka-Kuka M. Trimethylamine N-oxide preserves mitochondrial energy metabolism in rat model of right ventricle heart failure. 4th Annual UCLA Mitochondria Symposium - Los Angeles, CA. Online. November 5-6, 2020

  6. Zelencova D, Vilks K, Makrecka-Kuka M, Liepinsh E, Jaudzems K. Investigation of protective effects of fatty acid binding protein 3 against long-chain fatty acid derivative-induced damage. 6th International Electronic Conference on Medicinal Chemistry.  November 1-30, 2020

  7. Zvejniece B, Svalbe B, Stelfa G, Vavers E, Kupats E, Dambrova M, Zvejniece L “Behavioural phenotype of Sigma-1 receptor knock-out mice”. 78th International Scientific Conference of the University of Latvia. Riga, Latvia. April 23-24, 2020. Abstracts, Medicina Volume 56, Supplement 1, 2020., p 261. ISSN 1648-9233. https://medicina.lsmuni.lt/abstracts-of-the-international-scientific-conference-on-medicine-organized-within-the-frame-of-the-78th-international-scientific-conference-of-the-university-of-latvia/